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Article

Non-specific filtering of beta-distributed data.

BMC bioinformatics - 19 Jun 2014

Wang Xinhui, Laird Peter W, Hinoue Toshinori, Groshen Susan, Siegmund Kimberly D

Abstract excerpt

BACKGROUND: Non-specific feature selection is a dimension reduction procedure performed prior to cluster analysis of high dimensional molecular data. Not all measured features are expected to show biological variation, so only the most varying are selected for analysis. In DNA methylation studies, DNA methylation is measured as a proportion, bounded between 0 and 1, with variance a function of the mean. Filtering...

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Identifiers

PMID: 24943962
DOI: 10.1186/1471-2105-15-199
PMCID: PMC4230495

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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