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Article

Laminopathy-inducing mutations reduce nuclear import of expressed prelamin A.

The international journal of biochemistry & cell biology - 1 Aug 2014

Kiel T, Busch A, Meyer-Rachner A, Hübner S

Abstract excerpt

Lamins are structural components of the nuclear lamina and integral parts of the nucleoplasm. The tripartite domain structure partitions the molecule into an amino-terminal head, central rod and a carboxy-terminal tail domain. The tail domain contains a nuclear localization sequence and in most l...

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Source

Identifiers

PMID: 24943589
DOI: 10.1016/j.biocel.2014.05.035

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24943589-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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