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Article

Determination of DPYD enzyme activity in Korean population.

Therapeutic drug monitoring - 1 Apr 2015

Shin Joong-Gon, Kang Tae Sun, Cheong Hyun Sub, Shin Hee Jung, Park Hyun Joo, Na Han Sung, Shin Hyoung Doo, Chung Myeon Woo

Abstract excerpt

BACKGROUND: Dihydropyrimidine dehydrogenase (DPYD) is an enzyme that regulates the rate-limiting step in pyrimidine metabolism, especially catabolism of fluorouracil. This study was performed to analyze the association between DPYD genetic variants and DPYD enzyme activity in the Korean population. METHODS: We screened the genetic variants and analyzed the enzyme activity in 73 healthy Korean subjects (69 men and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24943064
DOI: 10.1097/FTD.0000000000000109

Genes

DPYD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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