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Article

PDF neuron firing phase-shifts key circadian activity neurons in Drosophila.

eLife - 17 Jun 2014

Guo Fang, Cerullo Isadora, Chen Xiao, Rosbash Michael

Abstract excerpt

Our experiments address two long-standing models for the function of the Drosophila brain circadian network: a dual oscillator model, which emphasizes the primacy of PDF-containing neurons, and a cell-autonomous model for circadian phase adjustment. We identify five different circadian (E) neurons that are a major source of rhythmicity and locomotor activity. Brief firing of PDF cells at different times of day...

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Identifiers

PMID: 24939987
DOI: 10.7554/eLife.02780
PMCID: PMC4092873

Genes

PDF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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