Evening Activity Termination Timing in Drosophila melanogaster: Effects of Pigment-Dispersing Factor-Containing Large and Small Ventrolateral Neurons.

Abstract excerpt

In animals, the brain contains circadian clock neurons that regulate activity rhythms. The fruit fly Drosophila melanogaster exhibits a bimodal activity pattern characterized by two peaks, in the morning (M) and evening (E), known as the M and E peaks. These activity peaks are orchestrated by a network of approximately 240 clock neurons. The neuropeptide pigment-dispersing factor (PDF) is expressed in two sets of...

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