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Article

A new approach for efficient genotype imputation using information from relatives.

BMC genomics - 17 Jun 2014

Sargolzaei Mehdi, Chesnais Jacques P, Schenkel Flavio S

Abstract excerpt

BACKGROUND: Genotype imputation can help reduce genotyping costs particularly for implementation of genomic selection. In applications entailing large populations, recovering the genotypes of untyped loci using information from reference individuals that were genotyped with a higher density panel is computationally challenging. Popular imputation methods are based upon the Hidden Markov model and have...

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PMID: 24935670
DOI: 10.1186/1471-2164-15-478
PMCID: PMC4076979

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