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Article

FISH: fast and accurate diploid genotype imputation via segmental hidden Markov model.

Bioinformatics (Oxford, England) - 1 Jul 2014

Zhang Lei, Pei Yu-Fang, Fu Xiaoying, Lin Yong, Wang Yu-Ping, Deng Hong-Wen

Abstract excerpt

MOTIVATION: Fast and accurate genotype imputation is necessary for facilitating gene-mapping studies, especially with the ever increasing numbers of both common and rare variants generated by high-throughput-sequencing experiments. However, most of the existing imputation approaches suffer from either inaccurate results or heavy computational demand. RESULTS: In this article, aiming to perform fast and accurate...

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Identifiers

PMID: 24618466
DOI: 10.1093/bioinformatics/btu143
PMCID: PMC4071209

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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