Article
Performance of compulsive behavior in rats is not a unitary phenomenon - validation of separate functional components in compulsive checking behavior.
The European journal of neuroscience - 1 Sept 2014
Tucci Mark C, Dvorkin-Gheva Anna, Johnson Eric, Cheon Paul, Taji Leena, Agarwal Arnav, Foster Jane, Szechtman Henry
Abstract excerpt
A previous analysis of the quinpirole sensitisation rat model of obsessive-compulsive disorder revealed that the behavioral phenotype of compulsive checking consists of three constitutive components - vigor of checking performance, focus on the task of checking, and satiety following a bout of checking. As confirmation of this analysis, the aim of the present study was to reconstitute, without quinpirole...
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