Article

Effects of D3-preferring agonist PD 128907 on compulsive behaviour and decision making as assessed by the 5C-CPT

2024-01-23

Abstract excerpt

<h4>Background</h4> Repetitive rituals in OCD patients result from pathological doubt, which has been linked to dysfunction in decision-making. First-line drug treatments for OCD are selective serotonin reuptake inhibitors; however, 40% of OCD patients do not respond to these. As brain activity patterns in OCD resemble those in schizophrenic patients, this suggests a dopaminergic component, supported by data show...

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Literature Corpus work: 6f00e79b-c088-5348-a7db-24e4f255408d
DOI: 10.1101/2024.01.22.576339

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