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Article

Excessive habit formation in schedule-induced polydipsia: Microstructural analysis of licking among rat strains and involvement of the orbitofrontal cortex.

Genes, brain, and behavior - 1 Mar 2019

Merchán A, Mora S, Gago B, Rodriguez-Ortega E, Fernández-Teruel A, Puga J L, Sánchez-Santed F, Moreno M, Flores P

Abstract excerpt

Schedule-induced polydipsia (SIP) is an animal model of compulsive drinking that selects for individual differences and varies across rat strains. The aim of this study was to investigate excessive habit formation by analyzing the SIP licking microstructure among rat strains, and to compare the brain areas activated by SIP in different populations. Wistar, Long Evans and Roman High- and Low-Avoidance rat strains...

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PMID: 29877027
DOI: 10.1111/gbb.12489

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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