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Article

MIF family members cooperatively inhibit p53 expression and activity.

PloS one - 1 Jan 2014

Brock Stephanie E, Rendon Beatriz E, Xin Dan, Yaddanapudi Kavitha, Mitchell Robert A

Abstract excerpt

The tumor suppressor p53 is induced by genotoxic stress in both normal and transformed cells and serves to transcriptionally coordinate cell cycle checkpoint control and programmed cell death responses. Macrophage migration inhibitory factor (MIF) is an autocrine and paracrine acting cytokine/growth factor that promotes lung adenocarcinoma cell motility, anchorage-independence and neo-angiogenic potential....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 24932684
DOI: 10.1371/journal.pone.0099795
PMCID: PMC4059697

Genes

MIF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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