Article
Mitochondrial DNA variation and virologic and immunological HIV outcomes in African Americans.
AIDS (London, England) - 24 Aug 2014
Aissani Brahim, Shrestha Sadeep, Wiener Howard W, Tang Jianming, Kaslow Richard A, Wilson Craig M
Abstract excerpt
OBJECTIVE: To evaluate the impact of mitochondrial DNA (mtDNA) haplogroups on virologic and immunological outcomes of HIV infection. DESIGN: HAART-naive African American adolescent participants to the Reaching for Excellence in Adolescent Care and Health study. METHODS: The mtDNA haplogroups were inferred from sequenced mtDNA hypervariable regions HV1 and HV2 and their predictive value on HIV outcomes were...
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