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Article

Constitutive activity of the androgen receptor.

Advances in pharmacology (San Diego, Calif.) - 1 Jan 2014

Chan Siu Chiu, Dehm Scott M

Abstract excerpt

Prostate cancer (PCa) is the most frequently diagnosed cancer in the United States. The androgen receptor (AR) signaling axis is central to all stages of PCa pathophysiology and serves as the main target for endocrine-based therapy. The most advanced stage of the disease, castration-resistant prostate cancer (CRPC), is presently incurable and accounts for most PCa mortality. In this chapter, we highlight the...

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Identifiers

PMID: 24931201
DOI: 10.1016/B978-0-12-417197-8.00011-0
PMCID: PMC4277179

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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