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Article

Mechanisms of persistent activation of the androgen receptor in CRPC: recent advances and future perspectives.

World journal of urology - 1 Jun 2012

Nadiminty Nagalakshmi, Gao Allen C

Abstract excerpt

BACKGROUND: The emergence of castration resistance has remained the primary obstacle in prostate cancer therapy for several decades. Mechanisms likely to be involved in castration-resistant progression have been studied extensively, but have failed to yield many meaningful and effective targets. The re-activation of the androgen receptor (AR) in castration-resistant prostate cancer (CRPC) is now recognized as the...

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Identifiers

PMID: 22009116
DOI: 10.1007/s00345-011-0771-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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