Article
HLA-G gene expression influenced at allelic level in association with end stage renal disease and acute allograft rejection.
Human immunology - 1 Aug 2014
Misra Maneesh Kumar, Pandey Shashi Kant, Kapoor Rakesh, Sharma Raj Kumar, Kapoor Rohit, Prakash Swayam, Agrawal Suraksha
Abstract excerpt
BACKGROUND: Human leukocyte antigen (HLA)-G is a non-classical major-histocompatibility complex class-I molecule associated with immunosuppressive function. We have evaluated the impact of HLA-G allele associated with untranslated-region (UTR)-haplotype in end stage renal disease (ESRD) and acute allograft rejection (AR) cases. The mRNA levels of different HLA-G isoforms were evaluated in ESRD and AR cases....
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