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Article

A twin study of depression and nicotine dependence: shared liability or causal relationship?

Journal of affective disorders - 15 Dec 2012

Edwards Alexis C, Kendler Kenneth S

Abstract excerpt

BACKGROUND: The nature of the relationship between major depression (MD) and phenotypes related to smoking behavior, including nicotine dependence (ND), is complicated. We present results from analyses comparing models wherein MD and ND are influenced by a shared latent factor to one in which causal pathways between phenotypes are examined. METHOD: Data were collected for 2906 adult male twins from a...

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Identifiers

PMID: 22901332
DOI: 10.1016/j.jad.2012.03.048
PMCID: PMC3483438

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