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Article

Advantages and disadvantages of conditional systems for characterization of essential genes in Toxoplasma gondii.

Parasitology - 1 Sept 2014

Jiménez-Ruiz Elena, Wong Eleanor H, Pall Gurman S, Meissner Markus

Abstract excerpt

The dissection of apicomplexan biology has been highly influenced by the genetic tools available for manipulation of parasite DNA. Here, we describe different techniques available for the generation of conditional mutants. Comparison of the advantages and disadvantages of the three most commonly used regulation systems: the tetracycline inducible system, the regulation of protein stability and site-specific...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24926834
DOI: 10.1017/S0031182014000559

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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