Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Conditional Protein Degradation System To Study Essential Gene Function in Cryptosporidium parvum

24 Aug 2020

Abstract excerpt

Cryptosporidium parvum and Cryptosporidium hominis are leading pathogens responsible for diarrheal disease (cryptosporidiosis) and deaths in infants and children below 5 years of age. There are no effective treatment options and no vaccine for cryptosporidiosis. Therefore, there is an urgent need to identify essential gene targets and uncover their biological function to accelerate the development of new and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amoebic Infections and Treatments
Share to Clostridium difficile and Clostridium perfringens research
Share to Parasitic Infections and Diagnostics

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32843543
DOI: 10.1128/mbio.01231-20

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 16 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Conditional Protein Degradation System To Study Essential Gene Function in Cryptosporidium parvumPMID 32843543Read ↗

Adaptation of the tetracycline-repressible system for modulating the expression of essential genes in <i>Cryptococcus neoformans</i>Semantic proximity Read ↗

A Novel Tool for the Generation of Conditional Knockouts To Study Gene Function across the Plasmodium falciparum Life CycleSemantic proximity Read ↗

Approaches to Study Proteins Encoded by Essential Genes.Semantic proximity Read ↗

Targeted CRISPR screens reveal genes essential for Cryptosporidium survival in the host intestineSemantic proximity Read ↗

Use of the Golden Gate Cloning Technique for Plasmid Construction to Generate Conditional Lethal Mutants in C. difficile.Semantic proximity Read ↗

The enteric pathogen <i>Cryptosporidium parvum</i> exports proteins into the cytoplasm of the infected host cellSemantic proximity Read ↗

Identification of ClpP Dual Isoform Disruption as an Antisporulation Strategy for Clostridioides difficile.Semantic proximity Read ↗

Advantages and disadvantages of conditional systems for characterization of essential genes in Toxoplasma gondii.Semantic proximity Read ↗

A scaleable inducible knockout system for studying essential gene function in the malaria parasiteSemantic proximity Read ↗

Constitutive expression of Cas9 and rapamycin-inducible Cre recombinase facilitates conditional genome editing in Plasmodium bergheiSemantic proximity Read ↗

Computational analysis of genes with lethal knockout phenotype and prediction of essential genes in archaea.Semantic proximity Read ↗

A toolbox for conditional control of gene expression in apicomplexan parasitesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.