Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[Genetic aberrations and new treatment strategies for pediatric acute myeloid leukemia].

[Rinsho ketsueki] The Japanese journal of clinical hematology - 1 Jan 2018

Shiba Norio

Abstract excerpt

The pathogenesis of acute myeloid leukemia (AML) is heterogeneous and caused by various chromosomal aberrations, gene mutations or epigenetic modifications, and deregulated or overregulated gene expression, leading to increased proliferation and decreased hematopoietic progenitor cell differentiation. Although most of these aberrations are correlated with prognosis, accurate risk stratification remains...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Child
Share to Chromosome Aberrations
Share to DNMT3A gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Profiling

Share to Leukemia, Myeloid, Acute

Share to Mutation

Share to Nucleophosmin

Share to Prognosis

Source

Identifiers

PMID: 30305534
DOI: 10.11406/rinketsu.59.2260

Genes

CBFA2T3
DNMT3A
GLIS2
KMT2A
NPM1
NUP98
TET2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[Genetic aberrations and new treatment strategies for pediatric acute myeloid leukemia].PMID 30305534Read ↗

Acute Myeloid Leukemia in Children: Emerging Paradigms in Genetics and New Approaches to TherapySemantic proximity Read ↗

Comprehensive molecular understanding of pediatric acute myeloid leukemia.Semantic proximity Read ↗

A Review in Childhood Acute Myeloid Leukemia: Diagnosis and Novel TreatmentSemantic proximity Read ↗

A concise review on the molecular genetics of acute myeloid leukemia.Semantic proximity Read ↗

A comprehensive review of genetic alterations and molecular targeted therapies for the implementation of personalized medicine in acute myeloid leukemia.Semantic proximity Read ↗

‘Acute myeloid leukemia: a comprehensive review and 2016 update’Semantic proximity Read ↗

[Acute myeloid leukemia: molecular pathogenesis and new therapeutic strategies].Semantic proximity Read ↗

Recent advances in the understanding and treatment of acute myeloid leukemiaSemantic proximity Read ↗

[Analysis of Genomic Landscape in Patients with Acute Myeloid Leukemia].Semantic proximity Read ↗

Uncommon cytogenetic abnormalities identifying high-risk acute myeloid leukemia in children.Semantic proximity Read ↗

Transcriptome analysis offers a comprehensive illustration of the genetic background of pediatric acute myeloid leukemia.Semantic proximity Read ↗

[THE CLINICAL SIGNIFICANCE OF GENETIC MUTATIONS IN ACUTE MYELOID LEUKEMIA].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.