[Clinicopathologic correlation and ALK rearrangement in adenocarcinoma of lung].

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Article

[Clinicopathologic correlation and ALK rearrangement in adenocarcinoma of lung].

Zhonghua bing li xue za zhi = Chinese journal of pathology - 1 Apr 2014

Liu Pingping, Wang Cuiping, Wu Shafei, Gao Jie, Zeng Xuan

Abstract excerpt

OBJECTIVE: To investigate ALK gene rearrangements in lung adenocarcinomas in correlation with clinicopathologic parameters including prognosis. METHODS: Fluorescence in situ hybridization (FISH) was used to detect ALK gene rearrangements in 53 cases of lung adenocarcinomas. Mutations in exons 18, 19, 20 and 21 of EGFR were analyzed by Scorpion amplification refractory mutation system (Scorpions ARMS). RESULTS: In...

Topics

Adenocarcinoma, Mucinous
Adult
Aged
Aged, 80 and over
Anaplastic Lymphoma Kinase
Carcinoma, Acinar Cell
Disease-Free Survival
ErbB Receptors
Exons
Female
Follow-Up Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Gene Rearrangement

Humans

Lung Neoplasms

Male

Middle Aged

Mutation

Neoplasm Recurrence, Local

Source

Open in PubMed

Identifiers

PMID: 24915814

Genes

ALK
EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-24915814-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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