Article
[Detection of ALK, ROS1 and RET fusion genes in non-small cell lung cancer patients and its clinicopathologic correlation].
Zhonghua bing li xue za zhi = Chinese journal of pathology - 1 Sept 2015
Zhong Shan, Zhang Haiping, Bai Dongyu, Gao Dehong, Zheng Jie, Ding Yi
Abstract excerpt
OBJECTIVE: To study the prevalence of ALK, ROS1 and RET fusion genes in non-small cell lung cancer (NSCLC), and its correlation with clinicopathologic features. METHODS: Formalin-fixed and paraffin-embedded tissue sections from samples of 302 patients with NSCLC were screened for ALK, ROS1, RET fusions by real-time polymerase chain reaction (PCR). All of the cases were validated by Sanger DNA sequencing. The...
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