Article
Features of anaplastic lymphoma kinase rearrangement in early-stage lung cancer: Analysis of a nationwide Japanese database.
Journal of surgical oncology - 1 Oct 2023
Matsuura Yosuke, Mun Mingon, Shintani Yasushi, Okami Jiro, Ito Hiroyuki, Ohtsuka Takashi, Mori Takeshi, Watanabe Shun-Ichi, Chida Masayuki, Endo Shunsuke, Nakanishi Ryoichi, Kadokura Mitsutaka, Suzuki Hidemi, Miyaoka Etsuo, Yoshino Ichiro, Date Hiroshi
Abstract excerpt
BACKGROUND AND OBJECTIVES: Anaplastic lymphoma kinase (ALK) rearrangement is a representative driver mutation in lung cancer. However, the biology of early-stage ALK-rearranged lung cancer remains unclear. We aimed to assess the clinicopathological features, prognostic implications, and influence of ALK rearrangement on the postoperative course in surgically resected lung cancer. METHODS: We retrospectively...
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