[Clinicopathological features of lung adenocarcinoma harboring anaplastic lymphoma kinase rearrangements].

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Article

[Clinicopathological features of lung adenocarcinoma harboring anaplastic lymphoma kinase rearrangements].

Zhonghua zhong liu za zhi [Chinese journal of oncology] - 1 Jun 2015

Dong Yujie, Zhou Lijuan, Wang Jinghui, Cai Yiran, Mu Jing, Zhang Haiqing

Abstract excerpt

OBJECTIVE: To analyze the clinicopathological characteristics of patients with anaplastic lymphoma kinase (ALK) rearrangements in lung adenocarcinoma, and the clinical therapy and prognosis of the patients. METHODS: Clinicopathological data of 34 cases of ALK-positive patients treated in the Beijing Chest Hospital from 2005 to 2014 were reviewed. The expression of ALK proteins in the resected tumors was detected...

Topics

Adenocarcinoma
Adenocarcinoma of Lung
Anaplastic Lymphoma Kinase
Exons
Female
Gene Rearrangement
Genes, erbB-1
Humans
Immunohistochemistry
Lung Neoplasms
Male
Middle Aged
Mucins
Mutation
Neoplasm Proteins
Polymerase Chain Reaction
Prognosis
Receptor Protein-Tyrosine Kinases

Source

Open in PubMed

Identifiers

PMID: 26463147

Genes

ALK
EGFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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