Article
Common genetic variants in the glucocorticoid receptor and the 11β-hydroxysteroid dehydrogenase type 1 genes influence long-term cognitive impairments in patients with Cushing's syndrome in remission.
The Journal of clinical endocrinology and metabolism - 1 Sept 2014
Ragnarsson Oskar, Glad Camilla A M, Berglund Peter, Bergthorsdottir Ragnhildur, Eder Derek N, Johannsson Gudmundur
Abstract excerpt
CONTEXT: Cognitive function is impaired in patients with Cushing's syndrome (CS) in remission. OBJECTIVE: The objective of the investigation was to study the effects of polymorphisms in genes associated with glucocorticoid (GC) sensitivity on cognitive function in patients with CS in long-term remission. DESIGN: This was a cross-sectional, case-controlled, single-center study. PATIENTS: Fifty-three patients with...
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