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Article

HDL and cholesterol handling in the brain.

Cardiovascular research - 1 Aug 2014

Vitali Cecilia, Wellington Cheryl L, Calabresi Laura

Abstract excerpt

Cholesterol is an essential component of both the peripheral nervous system and central nervous system (CNS) of mammals. Brain cholesterol is synthesized in situ by astrocytes and oligodendrocytes and is almost completely isolated from other pools of cholesterol in the body, but a small fraction can be taken up from the circulation as 27-hydroxycholesterol, or via the scavenger receptor class B type I. Glial...

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PMID: 24907980
DOI: 10.1093/cvr/cvu148

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