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Article

The study of severe cutaneous drug hypersensitivity reactions from a systems biology perspective.

Current opinion in allergy and clinical immunology - 1 Aug 2014

Perkins James R, Ayuso Pedro, Cornejo-García José A, Ranea Juan A

Abstract excerpt

PURPOSE OF REVIEW: Stevens-Johnson syndrome and toxic epidermal necrolysis are severe hypersensitivity reactions, the majority of which are drug induced. The underlying mechanisms are not fully understood. Here, we review recent findings concerning both mechanistic and genetic factors related to...

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Identifiers

PMID: 24905771
DOI: 10.1097/ACI.0000000000000076

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24905771-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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