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Article

A novel catechol-O-methyltransferase variant associated with human disc degeneration.

International journal of medical sciences - 1 Jan 2014

Gruber Helen E, Sha Wei, Brouwer Cory R, Steuerwald Nury, Hoelscher Gretchen L, Hanley Edward N

Abstract excerpt

BACKGROUND: Disc degeneration and its associated low back pain are a major health care concern causing disability with a prominent role in this country's medical, social and economic structure. Low back pain is devastating and influences the quality of life for millions. Low back pain lifetime pr...

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Topics

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Share to Catechol O-Methyltransferase
Share to COMT gene
Share to Genetic Association Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Intervertebral Disc Degeneration

Share to Low Back Pain

Share to Polymorphism, Single Nucleotide

Share to Sex Characteristics

Source

Open in PubMed Open full text

Identifiers

PMID: 24904231
DOI: 10.7150/ijms.8770
PMCID: PMC4045795

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24904231-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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