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Article

Association of catechol-O-methyltransferase genetic variants with outcome in patients undergoing surgical treatment for lumbar degenerative disc disease.

The spine journal : official journal of the North American Spine Society - 1 Nov 2010

Dai Feng, Belfer Inna, Schwartz Carolyn E, Banco Robert, Martha Julia F, Tighioughart Hocine, Tromanhauser Scott G, Jenis Louis G, Kim David H

Abstract excerpt

BACKGROUND CONTEXT: Surgical treatment for lumbar degenerative disc disease (DDD) has been associated with highly variable results in terms of postoperative pain relief and functional improvement. Many experts believe that DDD should be considered a chronic pain disorder as opposed to a degenerative disease. Genetic variation of the catechol-O-methyltransferase (COMT) gene has been associated with variation in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20863768
DOI: 10.1016/j.spinee.2010.07.387

Genes

COMT
LBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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