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Article

Genetic contribution of catechol-O-methyltransferase variants in treatment outcome of low back pain: a prospective genetic association study.

BMC musculoskeletal disorders - 21 May 2012

Omair Ahmad, Lie Benedicte Alexandra, Reikeras Olav, Holden Marit, Brox Jens Ivar

Abstract excerpt

BACKGROUND: Treatment outcome of low back pain (LBP) is associated with inter-individual variations in pain relief and functional disability. Genetic variants of catechol-O-methyltransferase (COMT) gene have previously been shown to be associated with pain sensitivity and pain medication. This study examines the association between COMT polymorphisms and 7-11 year change in Oswestry Disability Index (ODI) and...

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Identifiers

PMID: 22612913
DOI: 10.1186/1471-2474-13-76
PMCID: PMC3453507

Genes

LBP
COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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