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Article

αNAC inhibition of the FADD-JNK axis plays anti-apoptotic role in multiple cancer cells.

Cell death & disease - 5 Jun 2014

Zeng W, Zhang J, Qi M, Peng C, Su J, Chen X, Yuan Z

Abstract excerpt

Nascent polypeptide-associated complex α (αNAC) is reportedly overexpressed in several types of cancers and regulates cell apoptosis under hypoxic conditions in HeLa cells. The aim of our study was to investigate the apoptotic function of αNAC in cancer progression. First, we observed the cellula...

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Identifiers

PMID: 24901053
DOI: 10.1038/cddis.2014.192
PMCID: PMC4611707

Genes

FADD
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24901053-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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