Article
Genetic susceptibility in pneumoconiosis.
Toxicology letters - 5 Feb 2007
Yucesoy Berran, Luster Michael I
Abstract excerpt
A large number of cellular mediators such as cytokines, antioxidants and growth factors have been implicated in the pathogenesis of chronic inflammatory and fibrotic diseases. Common functional polymorphisms in these genes have been shown to influence individual susceptibility to these diseases. Silicosis, coal worker pneumoconiosis, progressive massive fibrosis and berylliosis are examples of fibrotic...
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