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Article

Novel somatic and germline mutations in intracranial germ cell tumours.

Nature - 10 Jul 2014

Wang Linghua, Yamaguchi Shigeru, Burstein Matthew D, Terashima Keita, Chang Kyle, Ng Ho-Keung, Nakamura Hideo, He Zongxiao, Doddapaneni Harshavardhan, Lewis Lora, Wang Mark, Suzuki Tomonari, Nishikawa Ryo, Natsume Atsushi, Terasaka Shunsuke, Dauser Robert, Whitehead William, Adekunle Adesina, Sun Jiayi, Qiao Yi, Marth Gábor, Muzny Donna M, Gibbs Richard A, Leal Suzanne M, Wheeler David A, Lau Ching C

Abstract excerpt

Intracranial germ cell tumours (IGCTs) are a group of rare heterogeneous brain tumours that are clinically and histologically similar to the more common gonadal GCTs. IGCTs show great variation in their geographical and gender distribution, histological composition and treatment outcomes. The inc...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24896186
DOI: 10.1038/nature13296
PMCID: PMC4532372

Genes

AKT1
KIT
BCORL1
CBL
KRAS
NRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24896186-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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