Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CNS Germ Cell Tumors: Molecular Advances, Significance in Risk Stratification and Future Directions

29 Apr 2024

Abstract excerpt

Central Nervous System Germ Cell Tumors (CNS GCTs) represent a subtype of intracranial malignant tumors characterized by highly heterogeneous histology. Current diagnostic methods in clinical practice have notable limitations, and treatment strategies struggle to achieve personalized therapy based on patient risk stratification. Advances in molecular genetics, biology, epigenetics, and understanding of the tumor...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related molecular mechanisms research
Share to Glioma Diagnosis and Treatment
Share to MicroRNA in disease regulation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38790424
DOI: 10.3390/brainsci14050445

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CNS Germ Cell Tumors: Molecular Advances, Significance in Risk Stratification and Future DirectionsPMID 38790424Read ↗

Advances in genetic abnormalities, epigenetic reprogramming, and immune landscape of intracranial germ cell tumorsSemantic proximity Read ↗

Intracranial Germ Cell Tumor in the Molecular EraSemantic proximity Read ↗

Pediatric primary central nervous system germ cell tumors of different prognosis groups show characteristic miRNome traits and chromosome copy number variationsSemantic proximity Read ↗

Primary Mediastinal and Testicular Germ Cell Tumors in Adolescents and Adults: A Comparison of Genomic Alterations and Clinical ImplicationsSemantic proximity Read ↗

Commentary: Novel Diagnostic Methods and Posttreatment Clinical Phenotypes Among Intracranial Germ Cell Tumors.Semantic proximity Read ↗

Novel molecular subtypes of intracranial germ cell tumors expand therapeutic opportunities.Semantic proximity Read ↗

Germline genetic landscape of pediatric central nervous system tumors.Semantic proximity Read ↗

Transcriptome and methylome analysis of CNS germ cell tumor finds its cell-of-origin in embryogenesis and reveals shared similarities with testicular counterparts.Semantic proximity Read ↗

Decoding testicular germ cell tumors: integrating risk, biology, and biomarkers into future care.Semantic proximity Read ↗

Precision Neuro-oncology: the Role of Genomic Testing in the Management of Adult and Pediatric Gliomas.Semantic proximity Read ↗

Novel Diagnostic Methods and Posttreatment Clinical Phenotypes Among Intracranial Germ Cell Tumors.Semantic proximity Read ↗

Cancer Predisposition Syndromes Associated With Pediatric High-Grade GliomasSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.