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Article

Genome-wide analysis of DNA copy number alterations and loss of heterozygosity in intracranial germ cell tumors.

Pediatric blood & cancer - 1 Apr 2014

Terashima Keita, Yu Alexander, Chow Wing-Yuk T, Hsu Wei-chun J, Chen Peikai, Wong Stephen, Hung Yeung Sam, Suzuki Tomonari, Nishikawa Ryo, Matsutani Masao, Nakamura Hideo, Ng Ho-Keung, Allen Jeffrey C, Aldape Kenneth D, Su Jack M, Adesina Adekunle M, Leung Hon-chiu E, Man Tsz-Kwong, Lau Ching C

Abstract excerpt

BACKGROUNDS: Intracranial germ cell tumors (GCTs) are rare and heterogeneous with very little is known about their pathogenesis and underlying genetic abnormalities. PROCEDURES: In order to identify candidate genes and pathways which are involved in the pathogenesis of these tumors, we have profiled 62 intracranial GCTs for DNA copy number alterations (CNAs) and loss of heterozygosity (LOH) by using single...

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Source

Identifiers

PMID: 24249158
DOI: 10.1002/pbc.24833

Genes

CCND2
PRDM14

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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