Article
Tracking in vivo dynamics of NK cells transferred in patients undergoing stem cell transplantation.
European journal of immunology - 1 Sept 2014
Killig Monica, Friedrichs Birte, Meisig Johannes, Gentilini Chiara, Blüthgen Nils, Loddenkemper Christoph, Labopin Myriam, Basara Nadezda, Pfrepper Christian, Niederwieser Dietger W, Uharek Lutz, Romagnani Chiara
Abstract excerpt
Haploidentical stem cell transplantation (haploSCT) offers an alternative treatment option for advanced leukemia patients lacking a HLA-compatible donor. Transfer of NK cells represents a promising therapeutic option in combination with SCT, as NK cells can promote graft versus leukemia with low risk of GVH disease. In this study, we show results from a phase I/II trial in which 24 acute myeloid leukemia patients...
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