Article
Nanomechanical phenotype of chondroadherin-null murine articular cartilage.
Matrix biology : journal of the International Society for Matrix Biology - 1 Sept 2014
Batista Michael A, Nia Hadi T, Önnerfjord Patrik, Cox Karen A, Ortiz Christine, Grodzinsky Alan J, Heinegård Dick, Han Lin
Abstract excerpt
Chondroadherin (CHAD), a class IV small leucine rich proteoglycan/protein (SLRP), was hypothesized to play important roles in regulating chondrocyte signaling and cartilage homeostasis. However, its roles in cartilage development and function are not well understood, and no major osteoarthritis-like phenotype was found in the murine model with CHAD genetically deleted (CHAD(-/-)). In this study, we used atomic...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
