Article
VGLL1 expression is associated with a triple-negative basal-like phenotype in breast cancer.
Endocrine-related cancer - 1 Aug 2014
Castilla María Ángeles, López-García María Ángeles, Atienza María Reina, Rosa-Rosa Juan Manuel, Díaz-Martín Juan, Pecero María Luisa, Vieites Begoña, Romero-Pérez Laura, Benítez Javier, Calcabrini Annarica, Palacios José
Abstract excerpt
Vestigial-like 1 (VGLL1) is a poorly characterized gene encoding a transcriptional co-activator structurally homologous to TAZ and YAP that modulates the Hippo pathway in Drosophila. In this study, we examined the expression of VGLL1 and its intronic miRNA, miR-934, in breast cancer. VGLL1 and miR-934 expression miRNA profiling was carried out on frozen samples of grade 3 invasive ductal carcinomas. VGLL1 protein...
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