Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetically shaping morphology of the filamentous fungus Aspergillus glaucus for production of antitumor polyketide aspergiolide A.

Microbial cell factories - 20 May 2014

Cai Menghao, Zhang Ying, Hu Wei, Shen Wei, Yu Zhenzhong, Zhou Weiqiang, Jiang Tao, Zhou Xiangshan, Zhang Yuanxing

Abstract excerpt

BACKGROUND: For filamentous fungi, the basic growth unit of hyphae usually makes it sensitive to shear stress which is generated from mechanical force and dynamic fluid in bioreactor, and it severely decreases microbial productions. The conventional strategies against shear-sensitive conundrum in fungal fermentation usually focus on adapting agitation, impeller type and bioreactor configuration, which brings high...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anthraquinones
Share to Antineoplastic Agents

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Aspergillus

Share to Batch Cell Culture Techniques

Share to Fungal Proteins

Share to Mutation

Share to Open Reading Frames

Source

Open in PubMed Open full text

Identifiers

PMID: 24886193
DOI: 10.1186/1475-2859-13-73
PMCID: PMC4039328

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetically shaping morphology of the filamentous fungus Aspergillus glaucus for production of antitumor polyketide aspergiolide A.PMID 24886193Read ↗

Characterization and control of fungal morphology for improved production performance in biotechnologySemantic proximity Read ↗

Exploring differential traits of lipid-producing stages of the wild type and morphologically engineered strain of Aspergillus oryzae by comparative kinetic modeling.Semantic proximity Read ↗

Enhancement of FK520 production in Streptomyces hygroscopicus var. ascomyceticus ATCC 14891 by overpressing the pathyway specific regulatory gene fkbR2Semantic proximity Read ↗

Modern morphological engineering techniques for improving productivity of filamentous fungi in submerged cultures.Semantic proximity Read ↗

Isolation of a fluffy mutant of Aspergillus niger from chemostat culture and its potential use as a morphologically stable host for protein production.Semantic proximity Read ↗

PilG is Involved in the Regulation of Twitching Motility and Antifungal Antibiotic Biosynthesis in the Biological Control Agent Lysobacter enzymogenes.Semantic proximity Read ↗

Genome Shuffling and Gentamicin-Resistance to Improve ε-Poly-L-Lysine Productivity of Streptomyces albulus W-156.Semantic proximity Read ↗

A novel locus for mycelial aggregation forms a gateway to improved Streptomyces cell factories.Semantic proximity Read ↗

Perturbing glycosylphosphatidylinositol (GPI)-anchor biosynthesis alters cell wall architecture and modulates fungal morphologySemantic proximity Read ↗

Lipid production by robust Aspergillus oryzae BCC7051 and a mathematical model describing its growth and lipid phenotypic traits.Semantic proximity Read ↗

Increased enzyme production under liquid culture conditions in the industrial fungus Aspergillus oryzae by disruption of the genes encoding cell wall α-1,3-glucan synthase.Semantic proximity Read ↗

Genome shuffling for phenotypic improvement of industrial strains through recursive protoplast fusion technology.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.