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Article

A novel locus for mycelial aggregation forms a gateway to improved Streptomyces cell factories.

Microbial cell factories - 1 Apr 2015

van Dissel Dino, Claessen Dennis, Roth Martin, van Wezel Gilles P

Abstract excerpt

BACKGROUND: Streptomycetes produce a plethora of natural products including antibiotics and anticancer drugs, as well as many industrial enzymes. Their mycelial life style is a major bottleneck for industrial exploitation and over decades strain improvement programs have selected production strains with better growth properties. Uncovering the nature of the underlying mutations should allow the ready transfer of...

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PMID: 25889360
DOI: 10.1186/s12934-015-0224-6
PMCID: PMC4391728

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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