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Article

Impact of Y181C and/or H221Y mutation patterns of HIV-1 reverse transcriptase on phenotypic resistance to available non-nucleoside and nucleoside inhibitors in China.

BMC infectious diseases - 5 May 2014

Guo Wei, Li Hanping, Zhuang Daomin, Jiao Liyan, Liu Siyang, Li Lin, Liu Yongjian, Gui Tao, Jia Lei, Li Jingyun

Abstract excerpt

BACKGROUND: The aim of this study was to investigate the role of K101Q, Y181C and H221Y emerging in HIV-1 reverse transcriptase with different mutations patterns in phenotypic susceptibility to currently available NNRTIs (nevirapine NVP, efavirenz EFV) and NRTIs (zidovudine AZT, lamivudine 3TC, stavudine d4T) in China. METHODS: Phenotype testing of currently available NNRTIs (NVP, EFV) and NRTIs (AZT, 3TC, d4T)...

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Identifiers

PMID: 24885612
DOI: 10.1186/1471-2334-14-237
PMCID: PMC4024112

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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