Article
Sequence analysis for detection of drug resistance in Mycobacterium tuberculosis complex isolates from the Central Region of Cameroon.
BMC microbiology - 3 May 2014
Tekwu Emmanuel Mouafo, Sidze Larissa Kamgue, Assam Jean-Paul Assam, Tedom Jean-Claude, Tchatchouang Serges, Makafe Gaëlle Guiewi, Wetewale Anne-Laure Tchokote, Kuaban Christopher, Eyangoh Sara, Ntoumi Francine, Beng Véronique N Penlap, Frank Matthias
Abstract excerpt
BACKGROUND: The potential of genetic testing to rapidly diagnose drug resistance has lead to the development of new diagnostic assays. However, prior to implementation in a given setting, the association of specific mutations with specific drug resistance phenotypes should be evaluated. The purpose of this study was to evaluate molecular markers in predicting drug resistance in the Central Region of Cameroon....
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