Article
Genetic association of complement receptor 1 polymorphism rs3818361 in Alzheimer's disease.
Alzheimer's & dementia : the journal of the Alzheimer's Association - 1 Jul 2011
Antúnez Carmen, Boada Mercè, López-Arrieta Jesús, Moreno-Rey Concha, Hernández Isabel, Marín Juan, Gayán Javier, González-Pérez Antonio, Real Luis M, Alegret Montserrat, Tárraga Lluis, Ramírez-Lorca Reposo, Ruiz Agustín
Abstract excerpt
Complement receptor 1 gene polymorphism rs3818361 was recently shown to increase the risk of Alzheimer's disease (AD). We performed an independent replication study of this genetic variant in 2,470 individuals from Spain. By applying an allelic model, we observed a trend toward an association between this marker and late-onset AD susceptibility in our case-control study (odds ratio = 1.114, 95% confidence...
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