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Article

Sequencing of LRP2 reveals multiple rare variants associated with urinary trefoil factor-3.

Journal of the American Society of Nephrology : JASN - 1 Dec 2014

McMahon Gearoid M, Olden Matthias, Garnaas Maija, Yang Qiong, Liu Xuan, Hwang Shih-Jen, Larson Martin G, Goessling Wolfram, Fox Caroline S

Abstract excerpt

Novel biomarkers are being investigated to identify patients with kidney disease. We measured a panel of 13 urinary biomarkers in participants from the Offspring Cohort of the Framingham Heart Study. Using an Affymetrix chip with imputation to 2.5 M single-nucleotide polymorphisms (SNPs), we conducted a GWAS of these biomarkers (n=2640) followed by exonic sequencing and genotyping. Functional studies in zebrafish...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24876117
DOI: 10.1681/ASN.2013111240
PMCID: PMC4243354

Genes

LRP2
TFF3
MAF
HAVCR1
RASSF8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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