Article
Characterization of human αβTCR repertoire and discovery of D-D fusion in TCRβ chains.
Protein & cell - 1 Jan 2014
Liu Peipei, Liu Di, Yang Xi, Gao Jing, Chen Yan, Xiao Xue, Liu Fei, Zou Jing, Wu Jun, Ma Juncai, Zhao Fangqing, Zhou Xuyu, Gao George F, Zhu Baoli
Abstract excerpt
The characterization of the human T-cell receptor (TCR) repertoire has made remarkable progress, with most of the work focusing on the TCRβ chains. Here, we analyzed the diversity and complexity of both the TCRα and TCRβ repertoires of three healthy donors. We found that the diversity of the TCRα repertoire is higher than that of the TCRβ repertoire, whereas the usages of the V and J genes tended to be...
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