Article

CD300e modulates metabolic programs in adipose tissue macrophages during obesity

2025-07-05

Abstract excerpt

Previous studies in monozygotic twins discordant for body mass index (BMI) revealed that obese individuals exhibit elevated expression of the immune receptor CD300e in white adipose tissue (WAT). Notably, CD300e levels decreased following weight loss, implicating its involvement in adipose tissue remodeling and metabolic regulation. To elucidate the functional role of CD300e, we employed a Cd300e knockout ( Cd300...

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Literature Corpus work: 7fd1f745-c36f-5f23-b742-a5a7021e3a0f
DOI: 10.1101/2025.07.02.662518

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