Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Regular bottlenecks and restrictions to somatic fusion prevent the accumulation of mitochondrial defects in Neurospora.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 5 Jul 2014

Bastiaans E, Aanen D K, Debets A J M, Hoekstra R F, Lestrade B, Maas M F P M

Abstract excerpt

The replication and segregation of multi-copy mitochondrial DNA (mtDNA) are not under strict control of the nuclear DNA. Within-cell selection may thus favour variants with an intracellular selective advantage but a detrimental effect on cell fitness. High relatedness among the mtDNA variants of an individual is predicted to disfavour such deleterious selfish genetic elements, but experimental evidence for this...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aging
Share to DNA, Mitochondrial

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Replication

Share to Genetic Variation

Share to Mitochondria

Share to Mutagenesis, Insertional

Share to Neurospora

Share to Selection, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 24864316
DOI: 10.1098/rstb.2013.0448
PMCID: PMC4032522

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Regular bottlenecks and restrictions to somatic fusion prevent the accumulation of mitochondrial defects in Neurospora.PMID 24864316Read ↗

Intracellular evolution of mitochondrial DNA (mtDNA) and the tragedy of the cytoplasmic commons.Semantic proximity Read ↗

A Genome-wide Screen Reveals that Reducing Mitochondrial DNA Polymerase Can Promote Elimination of Deleterious Mitochondrial Mutations.Semantic proximity Read ↗

Premeiotic instability of repeated sequences in Neurospora crassa.Semantic proximity Read ↗

Avoiding organelle mutational meltdown across eukaryotes with or without a germline bottleneck.Semantic proximity Read ↗

Association between variant plasmid formation and senescence in retroplasmid-containing strains of Neurospora spp.Semantic proximity Read ↗

Asexual transmission, non-suppressiveness and meiotic extinction of small plasmid-like derivatives of the mitochondrial DNA in Neurospora crassa.Semantic proximity Read ↗

The causes of mutation accumulation in mitochondrial genomes.Semantic proximity Read ↗

Suppression of cytoplasmic senescence in Neurospora.Semantic proximity Read ↗

Vegetative incompatibility in Neurospora: its effect on horizontal transfer of mitochondrial plasmids and senescence in natural populations.Semantic proximity Read ↗

Mitochondria: A Microcosm of Darwinian Competition.Semantic proximity Read ↗

Somatic deficiency causes reproductive parasitism in a fungus.Semantic proximity Read ↗

Evolutionary Trajectories are Contingent on Mitonuclear Interactions.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.