Article
Evolutionary Trajectories are Contingent on Mitonuclear Interactions.
Molecular biology and evolution - 4 Apr 2023
Biot-Pelletier Damien, Bettinazzi Stefano, Gagnon-Arsenault Isabelle, Dubé Alexandre K, Bédard Camille, Nguyen Tuc H M, Fiumera Heather L, Breton Sophie, Landry Christian R
Abstract excerpt
Critical mitochondrial functions, including cellular respiration, rely on frequently interacting components expressed from both the mitochondrial and nuclear genomes. The fitness of eukaryotic organisms depends on a tight collaboration between both genomes. In the face of an elevated rate of evolution in mtDNA, current models predict that the maintenance of mitonuclear compatibility relies on compensatory...
Topics
- DNA, Mitochondrial
- Mitochondria
- Eukaryota
- Genotype
- Genome, Mitochondrial
- Cell Nucleus