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Evolutionary Trajectories are Contingent on Mitonuclear Interactions.

Molecular biology and evolution - 4 Apr 2023

Biot-Pelletier Damien, Bettinazzi Stefano, Gagnon-Arsenault Isabelle, Dubé Alexandre K, Bédard Camille, Nguyen Tuc H M, Fiumera Heather L, Breton Sophie, Landry Christian R

Abstract excerpt

Critical mitochondrial functions, including cellular respiration, rely on frequently interacting components expressed from both the mitochondrial and nuclear genomes. The fitness of eukaryotic organisms depends on a tight collaboration between both genomes. In the face of an elevated rate of evolution in mtDNA, current models predict that the maintenance of mitonuclear compatibility relies on compensatory...

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PMID: 36929911
DOI: 10.1093/molbev/msad061
PMCID: PMC10072823

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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