Article
Association between variant plasmid formation and senescence in retroplasmid-containing strains of Neurospora spp.
Current genetics - 1 Apr 2001
Fox A N, Kennell J C
Abstract excerpt
Serial transfer of Neurospora strains harboring the Mauriceville and Varkud mitochondrial retroplasmids frequently displays erratic growth and senescence. Growth impairment is associated with the formation of variant forms of the retroplasmids that can integrate into the mitochondrial genome, resulting in mtDNA rearrangements and eventual loss of respiratory function. Here, we evaluate the rate at which variant...
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