Article
Does autophagy mediate age-dependent effect of dietary restriction responses in the filamentous fungus Podospora anserina?
Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 5 Jul 2014
van Diepeningen Anne D, Engelmoer Daniël J P, Sellem Carole H, Huberts Daphne H E W, Slakhorst S Marijke, Sainsard-Chanet Annie, Zwaan Bas J, Hoekstra Rolf F, Debets Alfons J M
Abstract excerpt
Autophagy is a well-conserved catabolic process, involving the degradation of a cell's own components through the lysosomal/vacuolar machinery. Autophagy is typically induced by nutrient starvation and has a role in nutrient recycling, cellular differentiation, degradation and programmed cell death. Another common response in eukaryotes is the extension of lifespan through dietary restriction (DR). We studied a...
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