Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hallmarks of stem cell aging

24 Jun 2025

Abstract excerpt

As organisms age, somatic stem cells progressively lose their ability to sustain tissue homeostasis and support regeneration. Although stem cells are relatively shielded from some cellular aging mechanisms compared with their differentiated progeny, they remain vulnerable to both intrinsic and extrinsic stressors. In this review, we delineate five cardinal features that characterize aged stem cells and examine...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Genetics, Aging, and Longevity in Model Organisms
Share to Pluripotent Stem Cells Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40562035
DOI: 10.1016/j.stem.2025.06.004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hallmarks of stem cell agingPMID 40562035Read ↗

Manifestations and mechanisms of stem cell aging.Semantic proximity Read ↗

When stem cells grow old: phenotypes and mechanisms of stem cell agingSemantic proximity Read ↗

The Mechanism of Stem Cell AgingSemantic proximity Read ↗

Stem Cell Aging in Lifespan and Disease: A State-of-the-Art ReviewSemantic proximity Read ↗

Why stem/progenitor cells lose their regenerative potentialSemantic proximity Read ↗

Adult Stem Cells and Diseases of AgingSemantic proximity Read ↗

Aging of Stem and Progenitor Cells: Mechanisms, Impact on Therapeutic Potential, and RejuvenationSemantic proximity Read ↗

Telomere, DNA damage, and oxidative stress in stem cell agingSemantic proximity Read ↗

Stem cells and healthy aging.Semantic proximity Read ↗

Tissue resident stem cells: till death do us partSemantic proximity Read ↗

Role of stem cells in ageing and age-related diseasesSemantic proximity Read ↗

Effect of aging on stem cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.